Page 4 - PaxGenBio Co., Ltd.
P. 4

TECHNOLIGY
           Proprietary patent technology MPCR-ULFA

          Multiplex PCR – Universal Lateral Flow Assay
           • Convergence of Multiplex Molecular Diagnosis and Rapid diagnostic test Technology
           • The proprietary technology of PaxGenBio, which can be combined with the universal probe of the NC membrane
             regardless of the sequence of PCR products.
           • South Korea, U.S. patent registration, application from seven foreign countries


          Gold-Strepto Avidin is combined with                               Combination of universal region of target
          biotin labeled PCR products amplifying                             amplification PCR product and universal
          the genomic target area.                                           probe.

          Nanogold also has the advantage of                                 Reaction line is turned to red by
          improving the ability to combine with the                          nanogold
          probe by facilitating the physical flow of
          PCR products.
                                            Sample Pad           Reaction line area


                             Loading Multiplex-  Conjugation Pad  Membrane    Absorption pad
                              PCR products         Lateral Flow   Lateral Flow






           Smart Molecular Diagnosis Technology MPCR-ULFA
          Existing Major Molecular Diagnostic Product Technology


            Nucleic acid    Target nucleic   Confirmation by  Conventional PCR
          extraction from a   acid amplification  electrophoresis  Advantage : Affordable price
             specimen                                                                          It is required to
                                                          Disadvantage : It takes a lot of labor/time  develop low-cost
                           Thermal cycler                                                      molecular
                           Target Nucleic Acid Amplification   Real-time PCR                   diagnostic products
                                                                                               with maintaining
                           and Real-Time Verification     Advantage : Easy of use
                                               RFU                                             user convenience
                                     Detector             Disadvantage : Difficult to do multiplex
                           Thermal cycler         Cycler  over 5 plexes with expensive reagents






            MPCR-ULFA                 Target nucleic acid amplification and   Convenient on-site confirmation of PCR
            (Universal Lateral Flow Assay)  confirmation using Lateral Flow Assay  results
                                                                      Use on inexpensive universal kit (membrane)
            New molecular diagnosis
            technology with low coast and     PCR              Patent No : 10-1727111 (UPAH Tech.)
                                              product
            convenience               Thermal cycler loading  Kit for   Patent No : 10-1795773 (CAO Tech.)
                                                    checking
                                                    results
           ▪ Rapid Multiplex Molecular Diagnosis System

             MPCR (Multiplex Polymerase Chain Reaction)
            • Multiple diagnosis possible
            • Simultaneous amplification of various disease-related genes  • Securing high productivity and price
                                                                       competitiveness
             ULFA (Universal Lateral Flow Assay array                • User convenience increase
            • Rapid diagnosis possible
            • Results interpretation within 10 to 20 minutes
   1   2   3   4   5   6   7   8   9